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Druggability reports

OpenDDE can generate comprehensive druggability assessment reports for any protein target. Reports are available in JSON (for programmatic access) and PDF (for sharing).

What’s in a report?

  • Target summary — Protein name, gene, organism, sequence length
  • Pocket analysis — All predicted pockets with scores, residue composition, and druggability assessment
  • Ligand landscape — Known compounds, their activity ranges, and clinical development stages
  • Safety signals — Data from Open Targets on known safety concerns
  • Overall assessment — A summary druggability score with rationale

Generating a report

  1. Navigate to a target page (e.g., /app/target/P00533)
  2. Click the “Report” link in the navigation
  3. View the report in the browser or click “Download PDF”

API access

# JSON report
curl http://localhost:8000/api/v1/report/P00533

# PDF report
curl http://localhost:8000/api/v1/report/P00533/pdf -o report.pdf

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